A New Class of Survival Regression Models with Cure Fraction

Semiparametric Transformation Models for Survival Data with a Cure Fraction

We propose a class of transformation models for survival data with a cure fraction. The class of transformation models is motivated by biological considerations, and it includes both the proportional hazards and the proportional odds cure models as two special cases. An efficient recursive algorithm is proposed to calculate the maximum likelihood estimators. Furthermore, the maximum likelihood ...

Evaluation of prognostic factors affecting long and short term survival rates of Hodgkin's lymphoma patients using the cure fraction models

Background and Aim: This study aimed to analyze the factors affecting time and experience of relapse in the patients with Hodgkin's lymphoma, using cure fraction. Material and Methods: This retrospective study included all the patients diagnosed as Hodgkin's lymphoma in the Center for oncology and hematology in Shafa Hospital in Ahwaz City from 2002 to 2012. We used survival analysis and cure f...

Frailty models with a cure fraction for modeling clustered discrete survival data

A Class of Semiparametric Mixture Cure Survival Models with Dependent Censoring.

Modern cancer treatments have substantially improved cure rates and have generated a great interest in and need for proper statistical tools to analyze survival data with non-negligible cure fractions. Data with cure fractions are often complicated by dependent censoring, and the analysis of this type of data typically involves untestable parametric assumptions on the dependence of the censorin...

A general class of Bayesian survival models with zero and nonzero cure fractions.

We propose a new class of survival models which naturally links a family of proper and improper population survival functions. The models resulting in improper survival functions are often referred to as cure rate models. This class of regression models is formulated through the Box-Cox transformation on the population hazard function and a proper density function. By adding an extra transforma...